NIMA-Interacting Peptidylprolyl Isomerase

Preferred Label : NIMA-Interacting Peptidylprolyl Isomerase;

MeSH definition : A highly-conserved peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated SERINE- or THREONINE-PROLINE (pSer/Thr-Pro) motifs and causes conformational changes in certain proteins associated with the CELL CYCLE. It displays a preference for an acidic residue N-terminal to the isomerized proline bond and regulates MITOSIS, possibly by attenuating the mitosis-promoting activity of NIMA-RELATED KINASE 1.;

MeSH synonym : Isomerase, NIMA-Interacting Peptidylprolyl; NIMA Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase, NIMA-Interacting; PIN1 Protein; Pin1 Peptidylprolyl Isomerase; Isomerase, Pin1 Peptidylprolyl; Peptidylprolyl Isomerase, Pin1; Peptidyl-Prolyl Cis-Trans Isomerase Pin1; Peptidyl Prolyl Cis Trans Isomerase Pin1;

MeSH Related Number : EC 5.2.1.8;

Details

Origin ID

D000072340;

UMLS CUI

C1744230;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Peptidyl-Prolyl Cis-Trans Isomerase NIMA-Interacting 1 [NCIt concept]
Record concept(s)
- NIMA-interacting peptidylprolyl isomerase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ESS1 protein, S cerevisiae [MeSH Supplementary Concept]
- PIN1 protein, human [MeSH Supplementary Concept]
- PIN1AT protein, Arabidopsis [MeSH Supplementary Concept]
- PIN4 protein, human [MeSH Supplementary Concept]
- Pin1 protein, malus domestica [MeSH Supplementary Concept]
- Pin1 protein, mouse [MeSH Supplementary Concept]
- Pin1 protein, xenopus [MeSH Supplementary Concept]
- dod protein, Drosophila [MeSH Supplementary Concept]
- parvA protein, E coli [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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