MeSH definition : An I-kappa B protein that inhibits the activity of dimeric NF-KAPPA B P50-REL complexes,
sequesters transcription factor NF-kappaB as an inactive complex in the cytoplasm;
and prevents NF-kappaB nuclear translocation and DNA binding.;
MeSH synonym : Inhibitor alpha, NF-KappaB; NF KappaB Inhibitor alpha; alpha, NF-KappaB Inhibitor; Major Histocompatibility Complex Enhancer-Binding Protein MAD3; Major Histocompatibility Complex Enhancer Binding Protein MAD3; IKappaB-alpha; IKappaB alpha; p40 Protein (IKappaB-alpha); I Kappa B-alpha Protein; I Kappa B alpha Protein; IKappaBalpha;
An I-kappa B protein that inhibits the activity of dimeric NF-KAPPA B P50-REL complexes,
sequesters transcription factor NF-kappaB as an inactive complex in the cytoplasm;
and prevents NF-kappaB nuclear translocation and DNA binding.