" /> BTB-POZ Domain - CISMeF





Preferred Label : BTB-POZ Domain;

MeSH definition : A homodimerization protein interaction domain occurring at the N terminus of proteins that contain multiple copies of either CYS2-HIS2 ZINC FINGERS or KELCH REPEATS. It is characterized by a tightly intertwined dimer with an extensive hydrophobic interface. A surface-exposed groove lined with conserved amino acids is formed at the dimer interface, suggesting a peptide-binding site. Many BTB proteins are transcriptional regulators that are thought to regulate CHROMATIN structure.;

MeSH synonym : BTB POZ Domain; BTB-POZ Domains; POxvirus and Zinc Finger Domain; BTB (POZ) Domain; Broad-Complex, Tramtrack and Bric a Brac Domain; Broad Complex, Tramtrack and Bric a Brac Domain; BTB Domain; BTB Domains; POZ Domain; POZ Domains;

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Keyword's position in hierarchy(ies) : arborescence

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A homodimerization protein interaction domain occurring at the N terminus of proteins that contain multiple copies of either CYS2-HIS2 ZINC FINGERS or KELCH REPEATS. It is characterized by a tightly intertwined dimer with an extensive hydrophobic interface. A surface-exposed groove lined with conserved amino acids is formed at the dimer interface, suggesting a peptide-binding site. Many BTB proteins are transcriptional regulators that are thought to regulate CHROMATIN structure.

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10/07/2025


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