AlkB Homolog 8, tRNA Methyltransferase

Preferred Label : AlkB Homolog 8, tRNA Methyltransferase;

MeSH definition : A dioxygenase and alkylation repair homolog that catalyzes the methylation of 5-carboxymethyl URIDINE to 5-methylcarboxymethyl uridine at the wobble position of the ANTICODON loop in TRANSFER RNA (tRNA) via its methyltransferase domain. It has a preference for tRNA (ARGININE) and tRNA (GLUTAMATE), and does not bind tRNA (LYSINE).;

MeSH synonym : Probable Alpha-Ketoglutarate-Dependent Dioxygenase ABH8; Probable Alpha Ketoglutarate Dependent Dioxygenase ABH8; tRNA (Carboxymethyluridine(34)-5-O)-Methyltransferase ABH8; Alkylated DNA Repair Protein Alkb Homolog 8; S-Adenosyl-L-Methionine-Dependent tRNA Methyltransferase ABH8; S Adenosyl L Methionine Dependent tRNA Methyltransferase ABH8;

Registry Number MeSH : EC 1.14.11.-;

Details

Origin ID

D000071503;

UMLS CUI

C4255106;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
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- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
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- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Alkb homolog 8, trna methyltransferase [OMIM gene]
- alkB homolog 8, tRNA methyltransferase [HGNC gene]
- alkB homolog 8, tRNA methyltransferase [ORDO Gene]
Record concept(s)
- AlkB Homolog 8, tRNA Methyltransferase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ALKBH8 protein, arabidopsis [MeSH Supplementary Concept]
- ALKBH8 protein, human [MeSH Supplementary Concept]
- ALKBH8 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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