AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase

Preferred Label : AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase;

MeSH definition : A dioxygenase and alkylation repair homolog that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. It can also repair alkylated DNA containing 1-ethenoadenine in vitro. It has highest affinity for double-stranded DNA.;

MeSH synonym : AlkB Homolog 2, Alpha Ketoglutarate Dependent Dioxygenase; Alkylated DNA Repair Protein AlkB Homolog 2; Oxy DC1 Protein; DNA Oxidative Demethylase ALKBH2; Alpha-ketoglutarate-Dependent Dioxygenase AlkB Homolog 2; Alpha ketoglutarate Dependent Dioxygenase AlkB Homolog 2;

Registry Number MeSH : EC 1.14.11.33;

UNII : EC 1.14.11.33;

Details

Origin ID

D000071499;

UMLS CUI

C4255063;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Alkb homolog 2, alpha-ketoglutarate-dependent dioxygenase [OMIM gene]
Record concept(s)
- AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ALKBH2 protein, arabidopsis [MeSH Supplementary Concept]
- ALKBH2 protein, human [MeSH Supplementary Concept]
- Alkbh2 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients