APOBEC Deaminases

Preferred Label : APOBEC Deaminases;

MeSH definition : A family of conserved cytidine deaminases that catalyze the DEAMINATION of CYTIDINE to URIDINE. They are characterized by N and C-terminal zinc-dependent catalytic domains and have important functions in RNA EDITING; EPIGENTIC PROCESSES; and the INNATE IMMUNE RESPONSE against viruses.;

MeSH synonym : Deaminases, APOBEC; APOBEC Family Proteins; APOBEC Enzymes; Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptides; AID-APOBEC Deaminases; AID APOBEC Deaminases; Deaminases, AID-APOBEC;

Registry Number MeSH : EC 3.5.4.5;

UNII : EC 3.5.4.5;

Details

Origin ID

D000071478;

UMLS CUI

C4277610;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- APOBEC Family Protein [NCIt concept]
Record concept(s)
- APOBEC Deaminases [MeSH concept]
Related MeSH Supplementary Concept(s)
- APOBEC2 protein, human [MeSH Supplementary Concept]
- APOBEC3 proteins, human [MeSH Supplementary Concept]
- Apobec2 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- APOBEC Family Protein [NCIt concept]

Keyword's position in hierarchy(ies) :

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