" /> Caspase Activation and Recruitment Domain - CISMeF





Preferred Label : Caspase Activation and Recruitment Domain;

MeSH definition : A homotypic protein interaction module of the death domain superfamily. It is composed of a bundle of six alpha-helices that is related in sequence and structure to the DEATH DOMAIN and DEATH EFFECTOR DOMAIN. The Caspase Activation and Recruitment Domain (CARD domain) typically associates with other CARD-containing proteins, forming either dimers or trimers. CARD domains may occur in isolation, or in combination with other domains in CARD signaling adaptor proteins and initiator CASPASES that function in APOPTOSIS.;

MeSH synonym : Caspase Recruitment Domains; Caspase Activation and Recruitment Domains; CARD Domains; Caspase Recruitment Domain; Recruitment Domain, Caspase; Recruitment Domains, Caspase; CARD Domain;

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A homotypic protein interaction module of the death domain superfamily. It is composed of a bundle of six alpha-helices that is related in sequence and structure to the DEATH DOMAIN and DEATH EFFECTOR DOMAIN. The Caspase Activation and Recruitment Domain (CARD domain) typically associates with other CARD-containing proteins, forming either dimers or trimers. CARD domains may occur in isolation, or in combination with other domains in CARD signaling adaptor proteins and initiator CASPASES that function in APOPTOSIS.

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03/05/2025


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