" /> Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - CISMeF





Preferred Label : Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha;

MeSH definition : A transcriptional co-activator for NUCLEAR RECEPTORS. It is characterized by an N-terminal LxxLL sequence, a region that interacts with PPAR GAMMA, and a C-terminal RNA RECOGNITION MOTIF. It increases expression of MITOCHONDRIAL UNCOUPLING PROTEIN to regulate genes involved in metabolic reprogramming in response to dietary restriction and the integration of CIRCADIAN RHYTHMS with ENERGY METABOLISM.;

MeSH synonym : Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 alpha; PPARGC1a Protein; PPARGC-1-alpha Protein; PPARGC 1 alpha Protein; PGC-1-alpha Protein; PGC 1 alpha Protein;

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A transcriptional co-activator for NUCLEAR RECEPTORS. It is characterized by an N-terminal LxxLL sequence, a region that interacts with PPAR GAMMA, and a C-terminal RNA RECOGNITION MOTIF. It increases expression of MITOCHONDRIAL UNCOUPLING PROTEIN to regulate genes involved in metabolic reprogramming in response to dietary restriction and the integration of CIRCADIAN RHYTHMS with ENERGY METABOLISM.

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31/07/2025


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