Preferred Label : Small Leucine-Rich Proteoglycans;
MeSH definition : A proteoglycan family (SLRPs) that is defined by a central domain which consists of
a variable number of repeats of the motif LXXLxLXXNxL, where L may be LEUCINE; ISOLEUCINE;
VALINE; or other hydrophobic amino acids. The N-terminal contains four conserved CYSTEINE
residues and may be modified depending on function. SLRPs provide structural support
to the EXTRACELLULAR MATRIX and are critical for regulating its assembly and dynamics
at CELL-MATRIX JUNCTIONS.;
MeSH synonym : Small Leucine Rich Proteoglycans; SLRP Proteoglycans; Small Leucine-Rich Repeat Proteoglycans; Small Leucine Rich Repeat Proteoglycans; Small Leucine-Rich Repeat Proteoglycan; Small Leucine Rich Repeat Proteoglycan; Small Leucine-Rich Proteoglycan; Leucine-Rich Proteoglycan, Small; Proteoglycan, Small Leucine-Rich; SLRP Proteoglycan; Proteoglycan, SLRP; Small Leucine Rich Proteoglycan;
A proteoglycan family (SLRPs) that is defined by a central domain which consists of
a variable number of repeats of the motif LXXLxLXXNxL, where L may be LEUCINE; ISOLEUCINE;
VALINE; or other hydrophobic amino acids. The N-terminal contains four conserved CYSTEINE
residues and may be modified depending on function. SLRPs provide structural support
to the EXTRACELLULAR MATRIX and are critical for regulating its assembly and dynamics
at CELL-MATRIX JUNCTIONS.