Preferred Label : Carbonic Anhydrase IX;
MeSH definition : A carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like
domain, a catalytic region, a single-pass transmembrane domain, and a short intracellular
tail. It functions as a dimer and is expressed primarily by cells of the GASTROINTESTINAL
TRACT; BILE DUCT EPITHELIUM; and GALL BLADDER. It is expressed at high levels in many
solid tumors, especially CLEAR CELL RENAL CARCINOMA, in response to CELL HYPOXIA.;
MeSH synonym : Carbonic Anhydrase 9; CAIX Protein;
Registry Number MeSH : EC 4.2.1.1;
UNII : EC 4.2.1.1;
Origin ID : D000071231;
UMLS CUI : C4255077;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
A carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like
domain, a catalytic region, a single-pass transmembrane domain, and a short intracellular
tail. It functions as a dimer and is expressed primarily by cells of the GASTROINTESTINAL
TRACT; BILE DUCT EPITHELIUM; and GALL BLADDER. It is expressed at high levels in many
solid tumors, especially CLEAR CELL RENAL CARCINOMA, in response to CELL HYPOXIA.
