Preferred Label : Pharmacogenomic Variants;
MeSH definition : Naturally occurring genetic variations associated with drug response (e.g., dosage,
extent and rate of metabolic processes). While these variants are not markers for
GENETIC PREDISPOSITION TO DISEASE they influence PHARMACOKINETICS and pharmacodynamics
and often occur on genes encoding drug metabolism enzymes and transporters (e.g.,
ANGIOTENSIN CONVERTING ENZYME; CYTOCHROME P-450 CYP2D6).;
MeSH synonym : Pharmacogenomic Variant; Variant, Pharmacogenomic; Variants, Pharmacogenomic; Pharmacokinetic Genetic Variants; Genetic Variant, Pharmacokinetic; Genetic Variants, Pharmacokinetic; Pharmacokinetic Genetic Variant; Pharmacogenetic Variants; Pharmacogenetic Variant; Variant, Pharmacogenetic; Variants, Pharmacogenetic;
Origin ID : D000071184;
UMLS CUI : C4277630;
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Naturally occurring genetic variations associated with drug response (e.g., dosage,
extent and rate of metabolic processes). While these variants are not markers for
GENETIC PREDISPOSITION TO DISEASE they influence PHARMACOKINETICS and pharmacodynamics
and often occur on genes encoding drug metabolism enzymes and transporters (e.g.,
ANGIOTENSIN CONVERTING ENZYME; CYTOCHROME P-450 CYP2D6).
