Preferred Label : ADAMTS Proteins;
MeSH definition : A subfamily of ADAM proteases that are distinguished by the presence of one or more
THROMBOSPONDIN type-1 repeats (TSRs). These are three-strand motifs that contain characteristic
TRYPTOPHAN, ARGININE, and CYSTEINE residues respectively. In contrast to ADAM proteins,
which reside on CELL MEMBRANES, ADAMTS proteases are secreted and function in the
EXTRACELLULAR MATRIX.;
MeSH synonym : Adam Metallopeptidases With Thrombospondin Type 1 Motif Proteins; A Disintegrin And Metalloproteinase With Thrombospondin Motifs Proteins; ADAMTS Proteases; A Disintegrin And Metalloproteinase With Thrombospondin Motifs Protein; ADAMTS Protease; Protease, ADAMTS; Adam Metallopeptidases With Thrombospondin Type 1 Motif Protein; ADAMTS Protein; Protein, ADAMTS;
DeCS synonym : ADAMTS-Like Proteins;
MeSH hyponym : ADAMTS Like Proteins; ADAMTSL Proteins; ADAMTS-Like Protein; ADAMTS Like Protein; Protein, ADAMTS-Like; ADAMTSL Protein; Protein, ADAMTSL;
Registry Number MeSH : EC 3.4.24.-;
Origin ID : D000071096;
UMLS CUI : C4277636;
Allowable qualifiers
Record concept(s)
Related MeSH Supplementary Concept(s)
Semantic type(s)
A subfamily of ADAM proteases that are distinguished by the presence of one or more
THROMBOSPONDIN type-1 repeats (TSRs). These are three-strand motifs that contain characteristic
TRYPTOPHAN, ARGININE, and CYSTEINE residues respectively. In contrast to ADAM proteins,
which reside on CELL MEMBRANES, ADAMTS proteases are secreted and function in the
EXTRACELLULAR MATRIX.