MeSH definition : A protein domain of about 70 amino acids in length that folds into a sandwich structure
consisting of a beta sheet, alpha helix, and C-terminal hairpin loop which forms a
hydrophobic methylated-DNA binding patch. It binds to methylated CPG ISLANDS in eukaryotes
and occurs with other DNA and CHROMATIN binding domains such as AT-HOOK MOTIFS in
eukaryotic DNA BINDING PROTEINS.;
A protein domain of about 70 amino acids in length that folds into a sandwich structure
consisting of a beta sheet, alpha helix, and C-terminal hairpin loop which forms a
hydrophobic methylated-DNA binding patch. It binds to methylated CPG ISLANDS in eukaryotes
and occurs with other DNA and CHROMATIN binding domains such as AT-HOOK MOTIFS in
eukaryotic DNA BINDING PROTEINS.
Allowable qualifiers