Preferred Label : Type VII Secretion Systems;
MeSH definition : Bacterial secretion systems found in bacteria that have a MYCOLIC ACID-containing
outer membrane such as MYCOBACTERIACEAE; Corynebacteriaceae; and NOCARDIACEAE. These
are also known as ESX secretion systems because the first to be discovered is involved
in secreting major virulence factors EsxA and EsxB. There are several subtypes of
T7SSs including ESX-1, ESX-2, ESX-3, ESX-4, and ESX-5 secretion systems. The subtypes
share some core components including an inner membrane channel-forming ATPase complex,
a membrane-anchored mycosin, and a second channel that spans the outer mycolic acid-containing
membrane.;
MeSH synonym : ESX Secretion Systems; Systems, ESX Secretion; Secretion Systems, Type VII; T7SS Secretion System; Secretion System, T7SS; System, T7SS Secretion; Type 7 Secretion Systems; Secretion Systems, Type 7; Secretion Systems, ESX; ESX Secretion System; Secretion System, ESX; System, ESX Secretion; Type 7 Secretion System; Type VII Secretion System;
Origin ID : D000069377;
UMLS CUI : C4042800;
Allowable qualifiers
- Record concept(s)
- Semantic type(s)
Bacterial secretion systems found in bacteria that have a MYCOLIC ACID-containing
outer membrane such as MYCOBACTERIACEAE; Corynebacteriaceae; and NOCARDIACEAE. These
are also known as ESX secretion systems because the first to be discovered is involved
in secreting major virulence factors EsxA and EsxB. There are several subtypes of
T7SSs including ESX-1, ESX-2, ESX-3, ESX-4, and ESX-5 secretion systems. The subtypes
share some core components including an inner membrane channel-forming ATPase complex,
a membrane-anchored mycosin, and a second channel that spans the outer mycolic acid-containing
membrane.
