Preferred Label : Type II Secretion Systems;
MeSH definition : Gram-negative bacterial secretion systems which carry out the secretion of folded
proteins.T2SSs secrete folded proteins from the PERIPLASMIC SPACE that have been exported
there by SEC TRANSLOCASE or TAT SECRETION SYSTEMS, or they secrete folded proteins
directly from the CYTOPLASM. The T2SSs have four substructures, an ATPase, an inner
membrane platform, a pseudopilin, and secretin, an outer membrane complex which is
a channel for secretion. (This bacterial secretin is not the same as the mammalian
hormone also named SECRETIN.);
MeSH synonym : T2SS Secretion System; Secretion System, T2SS; System, T2SS Secretion; Type 2 Secretion System; Bacterial Secretion System, Type II; Type II Secretion System; Type 2 Secretion Systems;
Origin ID : D000069178;
UMLS CUI : C4019282;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Record concept(s)
Semantic type(s)
Gram-negative bacterial secretion systems which carry out the secretion of folded
proteins.T2SSs secrete folded proteins from the PERIPLASMIC SPACE that have been exported
there by SEC TRANSLOCASE or TAT SECRETION SYSTEMS, or they secrete folded proteins
directly from the CYTOPLASM. The T2SSs have four substructures, an ATPase, an inner
membrane platform, a pseudopilin, and secretin, an outer membrane complex which is
a channel for secretion. (This bacterial secretin is not the same as the mammalian
hormone also named SECRETIN.)