calcimycin - CISMeF

Preferred Label : calcimycin;

MeSH definition : An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.;

MeSH synonym : 4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-((3,9,11-trimethyl-8-(1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, (6S-(6alpha(2S*,3S*),8beta(R*),9beta,11alpha))-;

MeSH hyponym : A-23187; A 23187; A23187; Antibiotic A23187; A23187, Antibiotic;

MeSH CAS label : 4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-((3,9,11-trimethyl-8-(1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, (6S-(6alpha(2S*,3S*),8beta(R*),9beta,11alpha))-;

MeSH Related Number : 52665-69-7 (Calcimycin);

Registry Number MeSH : 52665-69-7;

Wikipedia link : https://en.wikipedia.org/wiki/A23187;

Is substance : O;

UNII : 37H9VM9WZL;

InChIKey : HIYAVKIYRIFSCZ-CYEMHPAKSA-N;

Details

Origin ID

D000001;

UMLS CUI

C0000699;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Calcimycin [NCIt concept]
Pharmacological action(s)
- anti-bacterial agents [MeSH Descriptor]
- calcium ionophores [MeSH Descriptor]
Record concept(s)
- A-23187 [MeSH concept]
- calcimycin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 3-hydroxycezomycin [MeSH Supplementary Concept]
- 4-bromo-A-23187 [MeSH Supplementary Concept]
- cezomycin [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Calcimycin [NCIt concept]

Keyword's position in hierarchy(ies) :

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