" /> Hyperprolactinemia - CISMeF





Preferred Label : Hyperprolactinemia;

Symbol : HPRL;

CISMeF acronym : HPRL;

Type : Phenotype, molecular basis known;

Description : Hyperprolactinemia unrelated to pregnancy occurs in approximately 0.1 to 0.3% of the general population and may result in infertility, hypogonadism, and galactorrhea. Such nonphysiologic hyperprolactinemia is caused mainly by drugs or by tumors in the anterior pituitary gland, primarily prolactinomas (see 600634). However, 10 to 60% of patients with hyperprolactinemia who undergo MRI have normal findings (summary by Newey et al., 2013).;

Inheritance : Autosomal dominant; Autosomal recessive;

Molecular basis : Caused by mutation in the prolactin receptor gene (PRLR, 176761.0002);

Prefixed ID : #615555;

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30/07/2025


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