Preferred Label : Podoconiosis, susceptibility to;
Symbol : PDCOS;
CISMeF acronym : PDCOS;
Type : Phenotype or locus, molecular basis unknown;
Alternative titles and symbols : Nonfilarial elephantiasis of lower legs, susceptibility to; Endemic nonfilarial elephantiasis, susceptibility to; Lymphostatic verrucosis, susceptibility to;
Description : Podoconiosis, or endemic nonfilarial elephantiasis, is a noninfectious geochemical
disease characterized by edema of the foot and lower leg that progresses to severe
elephantiasis. It is a chronic and debilitating disorder that is a public health problem
in at least 10 countries in tropical Africa, Central America, and northern India.
Podoconiosis occurs among subsistence farmers and other occupational groups whose
feet are exposed over many years to red clay soil derived from alkalic volcanic rock.
However, podoconiosis develops only in a subgroup of exposed people, and studies have
shown familial clustering with high heritability (summary by Davey et al. (2007) and
Tekola Ayele et al. (2012)).;
Prefixed ID : %614590;
Origin ID : 614590;
UMLS CUI : C3281245;
See also inter- (CISMeF)
- Semantic type(s)
