Description : Trichotillomania (TTM) is a neuropsychiatric disorder characterized by chronic, repetitive,
or compulsive hair pulling resulting in noticeable hair loss. The activity causes
distress to the individual and often interferes with functioning. Affected individuals
may develop physical complications and often have overlapping psychologic disorders,
such as Tourette syndrome (GTS; 137580) or obsessive-compulsive disorder (OCD; 164230)
(review by Novak et al., 2009).;
Inheritance : Autosomal dominant; Multifactorial;
Molecular basis : Caused by mutation in the slit- and ntrk-like family, member 1 gene (SLITRK1, 609678.0001);