Preterm premature rupture of the membranes - CISMeF
Preterm premature rupture of the membranesOMIM Phenotype
Preferred Label : Preterm premature rupture of the membranes;
Symbol : PPROM;
CISMeF acronym : PPROM;
Type : Phenotype, molecular basis known;
Description : Preterm premature rupture of the membranes is defined as rupture of membranes before
37 weeks of gestation, which occurs in approximately 3% of all pregnancies and accounts
for about one-third of spontaneous preterm births (ACOG Practice Bulletin, 1998).
Srinivas and Macones (2005) reviewed the pathophysiology of PPROM and noted that familial
clustering and ethnic differences in the incidence of PPROM suggest possible genetic
influences.;