Cytochrome B(-245), alpha subunit

Preferred Label : Cytochrome B(-245), alpha subunit;

Symbol : CYBA;

CISMeF acronym : CYBA;

Type : Gene and phenotype, combined;

Alternative titles and symbols : Cytochrome B(558), alpha subunit; Cytochrome B light chain; p22-PHOX;

Included titles and symbols : Reactive oxygen species generation, decreased;

Description : The CYBA gene encodes the alpha subunit, also known as the light chain, of cytochrome b(-245), which is a component of the NADPH oxidase (NOX) complex responsible for the respiratory burst in phagocytes. The CYBB gene (300481) is an X-linked gene which encodes the cytochrome b beta subunit, also known as the heavy chain. Dinauer et al. (1990) and Schapiro et al. (1991) referred to the 22-kD gene product as p22-phox (for phagocyte oxidase). De Boer et al. (1992) referred to the product of the CYBA gene as the alpha subunit of cytochrome b(558) or p22-phox. They mentioned an international agreement on designations.;

Prefixed ID : 608508;

Details

Origin ID

608508;

UMLS CUI

C1413843;

Currated CISMeF NLP mapping
- cytochrome b-245 alpha chain [ORDO Gene]
NCIt concept(s)
- CYBA Gene [NCIt concept]
- CYBA wt Allele [NCIt concept]
- Cytochrome B-245 Light Chain [NCIt concept]
ORDO concept(s)
- cytochrome b-245 alpha chain [ORDO Gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- CYBA Gene [NCIt concept]
- CYBA gene [LOINC component]
- cytochrome b-245 alpha chain [ORDO Gene]
- cytochrome b-245 alpha chain [HGNC gene]

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