Preferred Label : Abdominal obesity-metabolic syndrome 1;
Symbol : AOMS1;
CISMeF acronym : AOMS1;
Type : Phenotype or locus, molecular basis unknown;
Alternative titles and symbols : Metabolic syndrome X;
Included titles and symbols : Abdominal obesity-metabolic syndrome quantitative trait locus 1; Metabolic syndrome, protection against;
Description : A clustering of abdominal obesity, high triglycerides, low levels of high density
lipoprotein cholesterol (HDLC), high blood pressure, and elevated fasting glucose
levels is sometimes called metabolic syndrome X (Reaven, 1988) or abdominal obesity-metabolic
syndrome (Bjorntorp, 1991). The syndrome may affect nearly 1 in 4 U.S. adults and
is considered a veritable epidemic (Ford et al., 2002). It is a major risk factor
for both diabetes mellitus (see 125853 and Haffner et al., 1992) and cardiovascular
disease (Isomaa et al., 2001). The etiology is complex, determined by the interplay
of both genetic and environmental factors. The prevalence varies substantially among
ethnic groups, with the highest rates in Mexican American women (Park et al., 2003).
Other factors influencing the metabolic syndrome include age, smoking, alcohol, diet,
and physical inactivity.;
Inheritance : Autosomal dominant;
Laboratory abnormalities : Elevated fasting glucose levels;
Prefixed ID : %605552;
Origin ID : 605552;
UMLS CUI : C4552048;
Currated CISMeF NLP mapping
- DO Cross reference
- HPO term(s)
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
