Description : Benign recurrent intrahepatic cholestasis is characterized by intermittent episodes
of cholestasis without progression to liver failure. The cholestatic attacks vary
in severity and duration and patients are asymptomatic between episodes, both clinically
and biochemically (van Mil et al., 2004).;
Inheritance : Autosomal recessive;
Molecular basis : Caused by mutation in the ATP-binding cassette, subfamily B, member 11 gene (ABCB11,
603201.0002);
Laboratory abnormalities : Normal or mildly increased serum gamma-GGT (231950); Conjugated hyperbilirubinemia; Increased alkaline phosphatase; Increased serum bile acids;