Ossification of the posterior longitudinal ligament of spine

Preferred Label : Ossification of the posterior longitudinal ligament of spine;

Symbol : OPLL;

CISMeF acronym : OPLL;

Type : Phenotype or locus, molecular basis unknown;

Description : Ossification of the posterior longitudinal ligament of the spine (OPLL) can cause spinal-cord compression (Ono et al., 1977; Tsuyama, 1984). Patients with OPLL frequently present with a severe myelopathy that can lead to tetraparesis. X-ray examination detects OPLL in 0.7 to 2.0% of adult outpatients with cervical disorders (Firooznia et al., 1982); the observed incidence increases to 3.7% in patients over 50 years of age (Ohtsuka et al., 1987).;

Inheritance : Autosomal recessive;

Prefixed ID : %602475;

Details

Origin ID

602475;

UMLS CUI

C1865343;

Currated CISMeF NLP mapping
- ossification of the posterior longitudinal ligament of spine [DO Concept]
- ossification of the posterior longitudinal ligament of the spine [MeSH concept]
- ossification of the posterior longitudinal ligament of the spine [MeSH Supplementary Concept]
DO Cross reference
- ossification of the posterior longitudinal ligament of spine [DO Concept]
HPO term(s)
- Abnormality of the vertebral column [HPO term]
- Autosomal recessive inheritance [HPO term]
- Diabetes mellitus [HPO term]
- Ectopic ossification [HPO term]
- Hyperreflexia [HPO term]
- Increased bone mineral density [HPO term]
- Myelopathy [HPO term]
- Spinal cord compression [HPO term]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- ossification of the posterior longitudinal ligament of spine [DO Concept]
- ossification of the posterior longitudinal ligament of the spine [MeSH Supplementary Concept]
- ossification of the posterior longitudinal ligament of the spine [MeSH concept]

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