" /> Type 1 diabetes mellitus 11 - CISMeF





Preferred Label : Type 1 diabetes mellitus 11;

Symbol : T1D11;

CISMeF acronym : IDDM11; T1D11;

Type : Phenotype or locus, molecular basis unknown;

Alternative titles and symbols : Insulin-dependent diabetes mellitus 11; Diabetes mellitus, insulin-dependent, 11; IDDM11;

Description : Field et al. (1996) used the symbol IDDM11 for a susceptibility locus for insulin-dependent diabetes mellitus located on 14q24.3-q31. The locus was identified by demonstration of significant linkage to microsatellite D14S67, using both maximum likelihood methods and affected sib pair methods. They claimed that this represented the strongest reported evidence for linkage to any IDDM locus outside the HLA region. The subset of families in which affected children did not show increased sharing of HLA genes provided most of the support for D14S67 linkage. There was significant linkage heterogeneity between the HLA-defined subsets of families, suggesting to Field et al. (1996) that;

Prefixed ID : %601208;

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03/05/2025


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