Preferred Label : Asthma, susceptibility to;
Type : Phenotype, molecular basis known;
Alternative titles and symbols : Asthma, bronchial; Asthma-related traits, susceptibility to;
Included titles and symbols : Asthma, protection against; Asthma, diminished response to antileukotriene treatment in;
Description : Bronchial asthma is the most common chronic disease affecting children and young adults.
It is a complex genetic disorder with a heterogeneous phenotype, largely attributed
to the interactions among many genes and between these genes and the environment.
Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing,
and dyspnea; bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge
test; serum IgE levels; atopy; and atopic dermatitis (Laitinen et al., 2001; Illig
and Wjst, 2002; Pillai et al., 2006). See 147050 for information on the asthma-associated
phenotype atopy.;
Inheritance : Autosomal dominant vs. multifactorial;
Prefixed ID : #600807;
Origin ID : 600807;
UMLS CUI : C1869116;
Automatic exact mappings (from CISMeF team)
- Asthma [MedDRA Preferred Term]
DO Cross reference
Genes related to phenotype
HPO term(s)
See also inter- (CISMeF)
Semantic type(s)