Spermatogenic failure, y-linked, 2

Preferred Label : Spermatogenic failure, y-linked, 2;

Symbol : SPGFY2;

CISMeF acronym : SPGFY2;

Type : Phenotype, molecular basis known;

Alternative titles and symbols : Spermatogenic arrest, y-linked; Oligozoospermia, nonobstructive, y-linked; Oligospermia, nonobstructive, y-linked; Azoospermia, nonobstructive, y-linked; Spermatogenic failure, nonobstructive, y-linked;

Included titles and symbols : Azoospermia factor regions; Azf regions;

Description : About 2 to 3% of human males are infertile because of defects in sperm function, primarily due to oligozoospermia (defined as less than 10-15 million sperm per mL of semen) or azoospermia (Hull et al., 1985). - Heterogeneity of Spermatogenic Failure For a discussion of Y-linked spermatogenic failure due to Sertoli cell-only syndrome, see 400042. For a discussion of phenotypic and genetic heterogeneity of spermatogenic failure, see SPGF1 (258150).;

Inheritance : Y-linked (Yq11.23);

Prefixed ID : #415000;

Details

Origin ID

415000;

UMLS CUI

C1839071;

Automatic exact mappings (from CISMeF team)
- USP9Y wt Allele [NCIt concept]
Currated CISMeF NLP mapping
- Y-Linked Spermatogenic Failure-2 [NCIt concept]
- Y-linked spermatogenic failure 2 [DO Concept]
- spermatogenic failure, nonobstructive, Y-Linked [MeSH concept]
- spermatogenic failure, nonobstructive, Y-Linked [MeSH Supplementary Concept]
DO Cross reference
- Y-linked spermatogenic failure 2 [DO Concept]
Genes related to phenotype
- Ubiquitin-specific protease 9, y chromosome [OMIM gene]
HPO term(s)
- Azoospermia [HPO term]
- Y-linked inheritance [HPO term]
ORDO concept(s)
- Partial chromosome Y deletion [ORDO Disease]
Related ORDO disease(s)
- Partial chromosome Y deletion [ORDO Disease]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Y-Linked Spermatogenic Failure-2 [NCIt concept]
- Y-linked spermatogenic failure 2 [DO Concept]
- spermatogenic failure, nonobstructive, Y-Linked [MeSH Supplementary Concept]
- spermatogenic failure, nonobstructive, Y-Linked [MeSH concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients