Sarcoma, synovial

Preferred Label : Sarcoma, synovial;

Type : Other, mainly phenotypes with suspected mendelian basis;

Description : Synovial sarcomas, which represent approximately 10% of all soft tissue sarcomas, are aggressive spindle cell sarcomas containing in some cases areas of epithelial differentiation. They consistently show a specific t(X;18)(p11.2;q11.2), which usually represents either of 2 gene fusions, SYT (600192)-SSX1 (312820) or SYT-SSX2 (300192), encoding putative transcriptional proteins differing at 13 amino acid positions (summary by Ladanyi et al., 2002). Synovial sarcoma, according to the experience of Enzinger and Weiss (1983), is the fourth most common type of soft tissue sarcoma. It usually develops in adolescents and young adults, is more common in males than in females, and has no racial predilection.;

Prefixed ID : 300813;

Details

Origin ID

300813;

UMLS CUI

C0039101;

Automatic exact mappings (from CISMeF team)
- Adult Synovial Sarcoma [NCIt concept]
- Childhood Synovial Sarcoma [NCIt concept]
- SSX family member 2 [HGNC gene]
- Synovial sarcoma NOS [ICD-9 code]
- synovial sarcoma, nos [ICD-O menu]
Currated CISMeF NLP mapping
- Synovial Sarcoma [NCIt concept]
- Synovial sarcoma [PASCAL descriptor]
- Synovial sarcoma [HPO term]
- Synovial sarcoma [MedDRA Preferred Term]
- Synovial sarcoma [ORDO Disease]
- Synovial sarcoma (disorder) [SNOMED CT concept]
- Synovial sarcoma (morphologic abnormality) [SNOMED CT concept]
- Synovial sarcoma NOS [MedDRA LLT]
- Synovial sarcoma, NOS [ICD-O code]
- sarcoma, synovial [MeSH Descriptor]
- sarcoma, synovial [MeSH concept]
- synovial sarcoma [Radlex concept]
- synovial sarcoma [Disease (Nov.)]
- synovial sarcoma [DO Concept]
- synovial sarcoma, nos [SNOMED Notion]
DO Cross reference
- synovial sarcoma [DO Concept]
Genes related to phenotype
- Sarcoma, synovial, X breakpoint 2 [OMIM gene]
HPO term(s)
- Somatic mutation [HPO term]
- Synovial sarcoma [HPO term]
ORDO concept(s)
- Synovial sarcoma [ORDO Disease]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Synovial Sarcoma [NCIt concept]
- Synovial sarcoma [MedDRA Preferred Term]
- Synovial sarcoma [HPO term]
- Synovial sarcoma [ORDO Disease]
- Synovial sarcoma [PASCAL descriptor]
- Synovial sarcoma (disorder) [SNOMED CT concept]
- Synovial sarcoma (morphologic abnormality) [SNOMED CT concept]
- Synovial sarcoma NOS [MedDRA LLT]
- Synovial sarcoma, NOS [ICD-O code]
- Synovioma [MedDRA LLT]
- sarcoma, synovial [MeSH Descriptor]
- sarcoma, synovial [MeSH concept]
- synovial sarcoma [Radlex concept]
- synovial sarcoma [DO Concept]
- synovial sarcoma [Disease (Nov.)]
- synovial sarcoma, nos [SNOMED Notion]
- synovioma [Radlex concept]

Keyword's position in hierarchy(ies) :

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