Type : Phenotype or locus, molecular basis unknown;
Alternative titles and symbols : Oculomotor apraxia, cogan type; Saccade initiation failure, congenital; COMA;
Description : Congenital oculomotor apraxia, first reported by Cogan (1952), is characterized by
(1) defective or absent horizontal voluntary eye movements, and (2) defective or absent
horizontal ocular attraction movements. Oculomotor apraxia occurs in ataxia-telangiectasia
(208900). Also see ataxia-oculomotor apraxia syndrome (208920; 606002). Oculomotor
apraxia has been observed in the neuronopathic form of Gaucher disease (type III;
231000) (Erikson and Wahlberg, 1985; Gross-Tsur et al., 1989).;