Preferred Label : Actinic prurigo;
CISMeF acronym : HPLE;
Type : Phenotype or locus, molecular basis unknown;
Alternative titles and symbols : Polymorphic light eruption, hereditary; HPLE;
Included titles and symbols : Juvenile spring eruption of ears;
Description : Hereditary polymorphic light eruption is a form of photosensitivity found in the American
Indians of the central plains of Canada and the United States and in the Indians of
Central and South America. The disorder has also been called familial actinic prurigo,
solar dermatitis, and hydroa aestivale. In northern latitudes, skin lesions appear
on exposed areas early in spring, become severe during the summer, and abate in the
fall. Usually the disorder appears in childhood with eczematous crusted eruptions
on the face and arms. Fissured, crusted exudative cheilitis develops on the lips,
especially the lower lip. The dorsum of the hands, the laterodorsal aspects of the
forearms, and the lower half of the arms often show excoriated papular and nodular
lesions. Children frequently have complicating pyoderma. Adults usually exhibit an
erythematous plaquelike eruption on the face and other exposed areas. The disease
is more severe in children than in adults. Glomerulonephritis can follow streptococcal
pyoderma (summary by Fusaro and Johnson, 1980).;
Inheritance : Autosomal dominant;
Prefixed ID : %174770;
Origin ID : 174770;
UMLS CUI : C0406217;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- HPO term(s)
- ORDO concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
