Preferred Label : Nail disorder, nonsyndromic congenital, 5;
Symbol : NDNC5;
CISMeF acronym : NDNC5;
Type : Phenotype or locus, molecular basis unknown;
Alternative titles and symbols : Onycholysis, hereditary distal; Onycholysis, partial, with scleronychia;
Description : Hereditary distal onycholysis is an autosomal dominant nail disorder characterized
by a decreased rate of growth of the nail, scleronychia, and a straight or concave
proximal edge of detachment. Clinical features may include palmoplantar hyperhydrosis
and marked sensitivity of the fingers to cold (summary by Bazex et al., 1990). Hereditary
distal onycholysis is referred to here as nonsyndromic congenital nail disorder-5
(NDNC5). For a list of other nonsyndromic congenital nail disorders and a discussion
of genetic heterogeneity, see NDNC1 (161050).;
Inheritance : Autosomal dominant;
Prefixed ID : %164800;
Origin ID : 164800;
UMLS CUI : C1833909;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- DO Cross reference
- HPO term(s)
- Semantic type(s)
- UMLS correspondences (same concept)
