Preferred Label : Cyclic neutropenia;
Type : Phenotype, molecular basis known;
Alternative titles and symbols : Cyclic hematopoiesis;
Description : Cyclic neutropenia is a rare disease characterized by regular 21-day cyclic fluctuations
in the number of blood neutrophils, monocytes, eosinophils, lymphocytes, platelets,
and reticulocytes. The recurrent severe neutropenia causes patients to experience
periodic symptoms of fever, malaise, mucosal ulcers, and, rarely, life-threatening
infections. The disease occurs both as a congenital disorder and in an acquired form,
with essentially identical phenotypic presentations (summary by Migliaccio et al.,
1990).;
Inheritance : Autosomal dominant;
Prefixed ID : #162800;
Origin ID : 162800;
UMLS CUI : C0221023;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
DO Cross reference
Genes related to phenotype
HPO term(s)
ORDO concept(s)
Semantic type(s)
UMLS correspondences (same concept)