Mesothelioma, malignant

Preferred Label : Mesothelioma, malignant;

Symbol : MESOM;

CISMeF acronym : MESOM;

Type : Phenotype, molecular basis known;

Description : Malignant mesothelioma is an aggressive neoplasm of the serosal lining of the chest etiologically linked to asbestos. It is diagnosed in approximately 2,000 to 3,000 individuals annually in the United States, most of whom die within 2 years of diagnosis (summary by Bott et al., 2011). See also 614327 for a tumor predisposition syndrome that may contribute to the development of malignant mesothelioma upon asbestos exposure and is caused by germline mutation in the BAP1 gene (603089) on chromosome 3p21.;

Inheritance : Somatic mutation;

Molecular basis : Susceptibility conferred by mutation in the WT1 gene (WT1, 607102.0016); Susceptibility conferred by mutation in the B-cell leukemia/lymphoma 10 gene (BCL10, 603517.0001);

Neoplasia : Mesothelioma;

Prefixed ID : #156240;

Details

Origin ID

156240;

UMLS CUI

C0345967;

Automatic exact mappings (from CISMeF team)
- Malignant peritoneal mesothelioma [ORDO Disease]
- Mesothelioma (malignant, clinical disorder) (disorder) [SNOMED CT concept]
- Mesothelioma, malignant [ICD-11 Extension code]
- Mesothelioma, malignant [ICD-9 code]
- Pleural mesothelioma [ORDO Disease]
- mesomerism [IUPAC Term]
- mesothelioma [MedlinePlus Topic]
Currated CISMeF NLP mapping
- Malignant Mesothelioma [NCIt concept]
- Malignant mesothelioma [PASCAL descriptor]
- Malignant mesothelioma [HPO term]
- Mesothelioma malignant [MedDRA Preferred Term]
- Mesothelioma malignant NOS [MedDRA LLT]
- Mesothelioma, Malignant [MeSH concept]
- Mesothelioma, Malignant [MeSH Descriptor]
- Mesothelioma, malignant [ICD-O code]
- Mesothelioma, malignant (morphologic abnormality) [SNOMED CT concept]
- malignant mesothelioma [DO Concept]
- malignant mesothelioma [Disease (Nov.)]
- mesothelioma, malignant [ICD-O menu]
- mesothelioma, malignant [SNOMED Notion]
DO Cross reference
- malignant mesothelioma [DO Concept]
Genes related to phenotype
- B-cell cll/lymphoma 10 [OMIM gene]
- Wt1 transcription factor [OMIM gene]
HPO term(s)
- Malignant mesothelioma [HPO term]
- Somatic mutation [HPO term]
ORDO concept(s)
- Pleural mesothelioma [ORDO Disease]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Malignant Mesothelioma [NCIt concept]
- Malignant mesothelioma [HPO term]
- Malignant mesothelioma [PASCAL descriptor]
- Mesothelioma (malignant, clinical disorder) (disorder) [SNOMED CT concept]
- Mesothelioma malignant [MedDRA Preferred Term]
- Mesothelioma malignant NOS [MedDRA LLT]
- Mesothelioma, Malignant [MeSH Descriptor]
- Mesothelioma, malignant [ICD-O code]
- Mesothelioma, malignant (morphologic abnormality) [SNOMED CT concept]
- malignant mesothelioma [DO Concept]
- malignant mesothelioma [Disease (Nov.)]
- mesothelioma, malignant [SNOMED Notion]

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