Legg-calve-perthes disease

Preferred Label : Legg-calve-perthes disease;

Symbol : LCPD;

CISMeF acronym : LCPD; LCP;

Type : Phenotype, molecular basis known;

Alternative titles and symbols : Perthes disease; Legg-perthes disease; LCP;

Description : Legg-Calve-Perthes disease is characterized by loss of circulation to the femoral head, resulting in avascular necrosis in a growing child. Clinical pictures of the disease vary, depending on the phase of disease progression through ischemia, revascularization, fracture and collapse, and repair and remodeling of the bone. The disease occurs more frequently in boys, and most patients tend to be shorter than their peers. Both familial and isolated cases of LCP have been reported (summary by Chen et al., 2004).;

Inheritance : Autosomal dominant vs. multifactorial;

Prefixed ID : #150600;

Details

Origin ID

150600;

UMLS CUI

C1442965;

Automatic exact mappings (from CISMeF team)
- Legg-Calve-Perthes disease [PASCAL descriptor]
- Legg-Calve-Perthes disease [DO Concept]
- Legg-Calve-Perthes disease [MedDRA LLT]
- Osteochondrosis of head of femur [ICD-11 More detail]
- Perthes disease [MedDRA Preferred Term]
- Posterior cruciate ligament [FMA entity]
- osteochondrosis [ICPC-2 Rubric]
- osteonecrosis [MedlinePlus Topic]
- posterior cruciate ligament [MeSH Descriptor]
Currated CISMeF NLP mapping
- Avascular necrosis of the capital femoral epiphysis [HPO term]
- Avascular necrosis of the capital femoral epiphysis (disorder) [SNOMED CT concept]
- Juvenile osteochondrosis of hip AND/OR pelvis (disorder) [Inactive SNOMED CT concept]
- Legg-Calve-Perthes disease [MeSH Descriptor]
- Legg-Calve-Perthes disease [MeSH concept]
- Legg-Calvé-Perthes disease [ORDO Disease]
- Perthes Disease [NCIt concept]
- Perthes disease [Disease (Nov.)]
- Perthes' disease [MedDRA LLT]
- avascular necrosis of capital femoral epiphysis [Radlex concept]
- juvenile osteochondrosis of hip and pelvis [SNOMED Notion]
DO Cross reference
- Legg-Calve-Perthes disease [DO Concept]
Genes related to phenotype
- Collagen, type II, alpha-1 [OMIM gene]
HPO term(s)
- Autosomal dominant inheritance [HPO term]
- Avascular necrosis of the capital femoral epiphysis [HPO term]
- Delayed skeletal maturation [HPO term]
- Multifactorial inheritance [HPO term]
- Short stature [HPO term]
ORDO concept(s)
- Legg-Calvé-Perthes disease [ORDO Disease]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Avascular necrosis of the capital femoral epiphysis [HPO term]
- Avascular necrosis of the capital femoral epiphysis (disorder) [SNOMED CT concept]
- Calve-Perthes disease [MedDRA LLT]
- Coxa plana [ICD-10 Sub-category]
- Coxa plana [MedDRA LLT]
- Coxa plana (disorder) [SNOMED CT concept]
- Juvenile osteochondrosis of head of femur [Legg-Calvé-Perthes] [ICD-10 Sub-category (who)]
- Juvenile osteochondrosis of head of femur [Legg-Calvé-Perthes] [ICD-10 Sub-category]
- Legg-Calve-Perthes disease [MeSH Descriptor]
- Legg-Calve-Perthes disease [MeSH concept]
- Legg-Calve-Perthes disease [MedDRA LLT]
- Legg-Calvé-Perthes disease [ORDO Disease]
- Perthes Disease [NCIt concept]
- Perthes disease [ACR pathology]
- Perthes disease [MedDRA Preferred Term]
- Perthes' disease [MedDRA LLT]
- Pseudocoxalgia [ICD-10 Sub-category]
- avascular necrosis of capital femoral epiphysis [Radlex concept]

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