Gamma-aminobutyric acid receptor, beta-3

Preferred Label : Gamma-aminobutyric acid receptor, beta-3;

Obsolete resource : true;

Alternative titles and symbols : Gabrb3; Gaba-a receptor, beta-3 polypeptideinsomnia;

Description : Gamma-aminobutyric acid (GABA) receptors are a family of proteins involved in the GABAergic neurotransmission of the mammalian central nervous system. GABRB3 is a member of the GABA-A receptor gene family of heteromeric pentameric ligand-gated ion channels through which GABA, the major inhibitory neurotransmitter in the mammalian brain, acts. GABA-A receptors are the site of action of a number of important pharmacologic agents including barbiturates, benzodiazepines, and ethanol (summary by Whiting et al., 1999). For additional general information about the GABA-A receptor gene family, see GABRA1 (137160).;

Details

Origin ID

137192;

UMLS CUI

C1414916;

Automatic exact mappings (from CISMeF team)
- gamma-aminobutyric acid type A receptor subunit beta3 [ORDO Gene]
False automatic mappings
- insomnia [Disease (Nov.)]
ORDO concept(s)
- gamma-aminobutyric acid type A receptor subunit beta3 [ORDO Gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- gamma-aminobutyric acid type A receptor subunit beta3 [HGNC gene]

Keyword's position in hierarchy(ies) :

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