Preferred Label : Dyslexia, susceptibility to, 1;
Symbol : DYX1;
CISMeF acronym : DYX1; DYX4; DYX7;
Type : Phenotype, molecular basis known;
Alternative titles and symbols : Word-blindness, congenital; Reading disability, specific, 1;
Included titles and symbols : Dyslexia, susceptibility to, 4; Dyslexia, susceptibility to, 7; DYX4; DYX7;
Description : Dyslexia is a disorder manifested by difficulty learning to read despite conventional
instruction, adequate intelligence, and sociocultural opportunity. It is among the
most common neurodevelopmental disorders, with a prevalence of 5 to 12%. Although
there is evidence for familial clustering and heritability, the disorder is considered
a complex multifactorial trait (Schumacher et al., 2007). - Genetic Heterogeneity
of Susceptibility to Dyslexia Additional dyslexia susceptibility loci include DYX2
(600202) on chromosome 6p21.1, DYX3 (604254) on chromosome 2p16-p15, DYX5 (606896)
on chromosome 3p12-q13, DYX6 (606616) on chromosome 18p11.2, DYX8 (608995) on chromosome
1p36-p34, and DYX9 (300509) on chromosome Xq27.3. See MAPPING for other possible dyslexia
susceptibility loci.;
Inheritance : Autosomal dominant;
Prefixed ID : #127700;
Origin ID : 127700;
UMLS CUI : C1851967;
Genes related to phenotype
- HPO term(s)
- Semantic type(s)
