Preferred Label : Alcohol dehydrogenase 1b, class I, beta polypeptide;
Symbol : ADH1B;
CISMeF acronym : ADH1B; ADH2;
Type : Gene and phenotype, combined;
Alternative titles and symbols : Alcohol dehydrogenase 2; ADH, beta subunit; ADH2;
Included titles and symbols : Aerodigestive tract cancer, squamous cell, alcohol-related, protection against;
Description : The ADH1B gene encodes the beta subunit of class I alcohol dehydrogenase (ADH) (EC
1.1.1.1), an enzyme that catalyzes the rate-limiting step for ethanol metabolism:
the oxidation of alcohol to acetaldehyde. Class 1 ADH is a homo- or heterodimeric
molecule, formed by the association of 3 types of class I ADH subunits, alpha (ADH1A;
103700), beta, and gamma (ADH1C; 103730) (Edenberg, 2007). For a general discussion
of ADH, including evolution of the class I ADH genes, see 103700.;
Prefixed ID : 103720;
Origin ID : 103720;
UMLS CUI : C1412236;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
