" /> Jagged 1 - CISMeF





Preferred Label : Jagged 1;

Symbol : JAG1;

CISMeF acronym : JAGL1; JAG1;

Type : Gene;

Alternative titles and symbols : JAGL1;

Description : Jagged-1 is a ligand of the Notch receptor (see Notch1, 190198), and their binding triggers a cascade of proteolytic cleavage that eventually leads to the release of the intracellular part of the receptor from the membrane, allowing it to translocate to the nucleus and activate transcription factors that play key roles in cell differentiation and morphogenesis (Guarnaccia et al., 2004).;

Ensembl ID : ENSG00000101384;

Prefixed ID : *601920;

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28/07/2025


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