Thyrotropin-releasing hormone receptor

Preferred Label : Thyrotropin-releasing hormone receptor;

Symbol : TRHR;

CISMeF acronym : TRHR;

Type : Gene;

Description : Thyrotropin-releasing hormone (TRH; 613879), a small neuropeptide, is widely distributed throughout the central and peripheral nervous system as well as in extraneural tissues. The peptide is synthesized in the hypothalamus and transported by the portal vascular system to the anterior pituitary where it acts on thyrotropic and lactotropic cells to promote secretion of TSH and prolactin, respectively. Thyrotropin-releasing hormone receptor is a G protein-coupled receptor that activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon the binding of TRH. The TRHR gene is expressed in the thyrotrope cells of the anterior pituitary.;

Ensembl ID : ENSG00000174417;

Prefixed ID : *188545;

Details

Origin ID

188545;

UMLS CUI

C1442761;

Currated CISMeF NLP mapping
- receptors, Thyrotropin-Releasing hormone [MeSH concept]
- receptors, thyrotropin-releasing hormone [MeSH Descriptor]
- thyrotropin releasing hormone receptor [ORDO Gene]
HGNC gene
- thyrotropin releasing hormone receptor [HGNC gene]
ORDO concept(s)
- thyrotropin releasing hormone receptor [ORDO Gene]
Phenotypes related
- Hypothyroidism, congenital, nongoitrous, 7 [OMIM Phenotype]
Related ORDO disease(s)
- Resistance to thyrotropin-releasing hormone syndrome [ORDO Disease]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- thyrotropin releasing hormone receptor [HGNC gene]

Keyword's position in hierarchy(ies) :

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