Cd3 antigen, gamma subunit

Preferred Label : Cd3 antigen, gamma subunit;

Symbol : CD3G;

CISMeF acronym : CD3G;

Type : Gene;

Alternative titles and symbols : T-cell antigen receptor complex, gamma subunit of t3; CD3-GAMMA; T3G;

Description : The alpha-beta heterodimeric T-cell antigen receptor binds antigen in association with major histocompatibility complex proteins on host cell surfaces. These 2 disulfide-linked glycoproteins, TCRA (186880) and TCRB (186930), are associated on T-cell surfaces with a complex of proteins called CD3 (formerly T3). Human CD3 consists of at least 4 proteins: gamma, delta (186790), epsilon (186830), and zeta (186780). Krissansen et al. (1986) found striking homology between the gamma and delta subunits.;

Ensembl ID : ENSG00000160654;

Prefixed ID : *186740;

Details

Origin ID

186740;

UMLS CUI

C1413223;

Automatic exact mappings (from CISMeF team)
- CD3 antigen, gamma chain [MeSH Supplementary Concept]
- CD3 gamma subunit of T-cell receptor complex [HGNC gene]
- CD3 gamma subunit of T-cell receptor complex [ORDO Gene]
- CD3G Gene [NCIt concept]
- CD3G wt Allele [NCIt concept]
- G/T Mismatch-Specific Thymine DNA Glycosylase [NCIt concept]
- T-Cell Surface Glycoprotein CD3 Gamma Chain [NCIt concept]
- TARP wt Allele [NCIt concept]
- TDG wt Allele [NCIt concept]
- triiodothyronine glucuronide [MeSH Supplementary Concept]
HGNC gene
- CD3 gamma subunit of T-cell receptor complex [HGNC gene]
Matching ORDO disease(s)
- Combined immunodeficiency due to CD3gamma deficiency [ORDO Disease]
NCIt concept(s)
- CD3G Gene [NCIt concept]
- CD3G wt Allele [NCIt concept]
- T-Cell Surface Glycoprotein CD3 Gamma Chain [NCIt concept]
ORDO concept(s)
- CD3 gamma subunit of T-cell receptor complex [ORDO Gene]
Phenotypes related
- Immunodeficiency 17 [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- CD3 gamma subunit of T-cell receptor complex [HGNC gene]
- CD3G Gene [NCIt concept]

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