Crystallin, gamma-s

Preferred Label : Crystallin, gamma-s;

Symbol : CRYGS;

CISMeF acronym : CRYGS;

Type : Gene;

Alternative titles and symbols : Crystallin, gamma-8; CRYG8;

Description : Three major classes of crystallins, alpha (see 123660), beta (see 123610), and gamma, are common to the eye lens throughout all vertebrates. The beta and gamma classes are made up of homologous proteins and constitute the beta/gamma crystallin superfamily. One group of gamma crystallins (see 123660) affect early eye and lens development; gamma-S crystallin (formerly beta-S; see Zarina et al., 1992) is expressed late but abundantly in the ocular lens. It is also expressed outside the lens, particularly in the mature retina and cornea. In contrast to the beta-crystallins which associate in various combinations to form low or high molecular weight aggregates, gamma-S is, like the other gamma-crystallins, a monomeric protein (summary by Sun et al., 2005).;

Ensembl ID : ENSG00000213139;

Prefixed ID : *123730;

Details

Origin ID

123730;

UMLS CUI

C1413740;

Automatic exact mappings (from CISMeF team)
- crystallin gamma A [HGNC gene]
- crystallin gamma S [HGNC gene]
- crystallin gamma S [ORDO Gene]
- crystallin gammaE [MeSH Supplementary Concept]
- crystallin gammaE [MeSH concept]
- gamma-crystallins [MeSH Descriptor]
HGNC gene
- crystallin gamma S [HGNC gene]
ORDO concept(s)
- crystallin gamma S [ORDO Gene]
Phenotypes related
- Cataract 20, multiple types [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- crystallin gamma S [ORDO Gene]
- crystallin gamma S [HGNC gene]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients