LOINC display name : Neutrophil.fMLP and PMA stimulated DHR panel FC;
LOINC long common name : Neutrophil.fMLP and PMA stimulated DHR panel by Flow cytometry (FC);
LOINC short name : Neut fMLP PMA stim DHR Pnl Patient FC;
LOINC description : The phorbol myristate acetate (PMA) and N-formyl-methionyl-leucyl-phenylalanine (fMLP)
stimulated neutrophil dihydrorhodamine (DHR) test assesses neutrophil activation and
NADPH oxidase function when stimulated by PMA and fMLP (different populations of neutrophils
are stimulated by PMA and fMLP, respectively). This test is used to diagnose chronic
granulomatous disease (CGD) and complete myeloperoxidase deficiency; monitor chimerism
and NADPH oxidase function after stem cell transplant, assess NADPH oxidase activity
prior to transplant; identify and monitor chromosome X inactivation changes with age
in carrier females with X-linked CGD; and diagnose Rac2 deficiency. To report results
for the fMLP stimulated neutrophil DHR test alone, use [LOINC: 98123-3]. To report
results for the PMA stimulated neutrophil DHR test alone, use [LOINC: 98124-1].;
Has component