Preferred Label : Hereditary cancer multigene analysis:Find:Pt:Bld/Tiss:Doc:Molgen;
LOINC status : ACTIVE;
LOINC display name : Hereditary cancer multigene analysis Molgen Doc (Bld/Tiss);
LOINC long common name : Hereditary cancer multigene analysis in Blood or Tissue by Molecular genetics method;
LOINC short name : Hereditary Cancer Multigene Anl Bld/T;
LOINC description : Multigene testing for heritable germline mutations in genes associated with cancer
in various organ systems, including breast and gynecologic (breast, ovarian, uterine),
gastrointestinal (colorectal, gastric, pancreatic), endocrine (thyroid, paraganglioma/pheochromocytoma,
parathyroid, pituitary), genitourinary (renal/urinary tract, prostate), skin (melanoma,
basal cell carcinoma), brain/nervous system, and bone/soft tissue (sarcoma) & blood
(myelodysplastic syndrome/leukemia). Testing is performed to confirm a diagnosis and
help guide treatment and management decisions. Identification of a disease-causing
variants may also used to inform at-risk relatives. Approximately 5-10 percent of
cancers are thought to be hereditary.[PMID: 15637391] This test is not appropriate
for the detection of somatic mutations in tumor tissue since it is focused on heritable
germline mutations.;
Origin ID : 97656-3;
UMLS CUI : C5452449;
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