LOINC display name : SARS-CoV-2 (COVID-19) neut ab pVNT Ql (S);
LOINC long common name : SARS-CoV-2 (COVID-19) neutralizing antibody [Presence] in Serum by pVNT;
LOINC short name : SARS-CoV-2 NAb Ser Ql pVNT;
LOINC description : Qualitative results for SARS Coronavirus 2 (SARS-CoV-2) virus neutralizing antibodies
in serum by pVNT (pseudovirus neutralization test). Neutralizing antibody testing
is performed to determine whether the antibodies produced after SARS-CoV-2 infection
or in response to a vaccination are able to neutralize the virus and prevent infection
or re-infection. Different methods can be used to determine the presence of neutralizing
antibodies, including VNT (virus neutralization test) and pVNT, which are represented
in LOINC as the Method Neutralization and pVNT, respectively. The pVNT method for
SARS-CoV-2 neutralizing antibody testing uses recombinant pseudoviruses that incorporate
the S protein from SARS-CoV-2, whereas VNT uses SARS-CoV-2 virus from a clinical isolate
or recombinant SARS-CoV-2 expressing reporter proteins.;