LOINC display name : CD11a, CD11b, and CD18 phenotyping panel Ql (Bld);
LOINC long common name : CD11a, CD11b, and CD18 phenotyping panel - Blood Qualitative;
LOINC short name : CD11a CD11b CD18 Pnl Bld;
LOINC description : Flow cytometric immunophenotyping evaluation for presence or absence of the CD11/CD18
complex using monoclonal antibodies directed against the CD11 isoforms, CD11a and
CD11b, and CD18 antigens. Defects in CD18 expression lead to either very low or no
surface membrane expression of alpha chains CD11a, CD11b, and CD11c. Testing is performed
for the diagnosis of leukocyte adhesion deficiency syndrome type 1 (LAD-1), an autosomal
recessive disorder caused by mutations in the common chain (CD18) of the beta2-integrin
family.;