Antithrombin:RelCCnc:Pt:PPP:Qn:Chromo.no addition of heparin

Preferred Label : Antithrombin:RelCCnc:Pt:PPP:Qn:Chromo.no addition of heparin;

LOINC status : ACTIVE;

LOINC display name : Antithrombin Chromo.no addition of heparin (PPP) [Rel catalytic activity/Vol];

LOINC long common name : Antithrombin in Platelet poor plasma by Chromo.no addition of heparin;

LOINC short name : AT III PPP Chromo.no added heparin;

LOINC description : This term represents an antithrombin (AT) assay which, in contrast to typical AT assays, is performed in the ABSENCE of heparin. This assay is also known as Progressive antithrombin assay. It is used to identify type IIb AT deficiency, which is caused by a mutation in the AT heparin binding site (HBS). In type IIb AT deficiency, AT activity is reduced in the presence of heparin but is normal in the absence of heparin.[PMID: 19141163] This term was created for, but is not limited in use to, the Biophen Antithrombin 5 assay's VARIANT Method, which is performed without heparin. In patients with type IIb AT deficiency, AT activity is expected to be normal in patients with an HBS mutation.;

Details

Origin ID

91120-6;

UMLS CUI

C4738175;

Has component
- Antithrombin [LOINC component]
Has method
- Chromo.no addition of heparin [LOINC method]
- Chromogenic (Enzyme) [LOINC method]
Has property
- Relative catalytic concentration [LOINC Property]
Has system
- Platelet poor plasma [LOINC System]
Has time aspect
- Point in time (spot) [LOINC time aspect]
Semantic type(s)
- Clinical Attribute [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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