LOINC display name : Neutrophils.immature/Neutrophils.total (Bld) [Pure # fraction];
LOINC long common name : Neutrophils.immature/Neutrophils.total [Pure number fraction] in Blood;
LOINC short name : Neut.immature/Neut.total NFr.DF Bld;
LOINC description : When evaluating newborns for sepsis, it has been found that the ratio of immature
neutrophils to total neutrophils (I/T) in the peripheral blood can be a useful indicator.
Several parameters are used to predict infection including a low white blood cell
count (WBC), a low absolute neutrophil count (ANC), and a high immature neutrophil
to total neutrophil count (I/T). Because of the expected variability of white blood
cell counts in the first four hours after birth, it is recommended that the neutrophil
count be done after the baby is four hours old. Low ANC indicate the highest risk
for sepsis regardless of the I/T. High I/T levels only indicate a high likelihood
of infection if the ANC is low. However, the effect of the I/T at various levels of
ANC is less consistent. When the I/T is less than 0.15, the likelihood of infection
is low regardless of the ANC.[PMID: 24503598];