LOINC long common name : Carbapenemase [Presence] in Isolate;
LOINC short name : Carbapenemase Islt Ql;
LOINC description : The detection of carbapenemase-producing isolates by various phenotypic methods, including
the Modified Hodge Test (MHT) and Carbapemenase Inactivation Method (CIM). In MHT,
carbapenemase production is detected when the test isolate produces the enzyme and
allows growth of a carbapenem susceptible strain (E.coli ATCC 25922) towards a carbapenem
disk. The result is a characteristic cloverleaf-like indentation. For CIM, a disk
containing the indicator antibiotic meropenem is incubated for 2 hours in a bacterial
suspension of the isolate. When the isolate produces carbapenemase, the meropenem
in the disk is inactivated allowing uninhibited growth of an indicator strain.[PMID:
28476242];
Has component