LOINC display name : Porcine epidemic diarrhea virus whole genome sequence Nom (Isol);
LOINC long common name : Porcine epidemic diarrhea virus whole genome [Nucleotide sequence] in Isolate by Sequencing;
LOINC short name : PEDV whole genome Islt-Seq;
LOINC description : Porcine Epidemic Diarrhea Virus (PEDv) is a large-enveloped RNA virus, which is a
member of the genus Alphacoronavirus within the Coronaviridae family. The complete
PEDv genome consists of 5 gene segments: open reading frame 1 (ORF1), spike (S), envelope
(E), membrane (M), and nucleocapsid (N). It is encapsulated by a single N protein.
The S protein is the major envelope type I glycoprotein of the virion and contributes
to the stimulation of neutralizing antibodies in the infected host. Its association
to adapted growth in vitro and attenuation in vivo lends itself to use for genetic
comparison among PEDV isolates and effective vaccines. The M protein is required for
assembly and can also induce the production of virus-neutralizing antibodies. The
E protein contributes to coronavirus budding. The N protein has functions associated
with viral replication and pathogenesis.;
Has component