LOINC display name : Presumptive Rh Molgen Nom (Sal);
LOINC long common name : Presumptive Rh [Type] in Saliva (oral fluid) by Molecular genetics method;
LOINC short name : Rh.presumptive Sal by Molgen;
LOINC description : The presumptive (predicted) Rh factor for the D antigen (Rh positive or Rh negative)
based on genetic analysis of the RHD gene. Hematopoietic stem cell transplant donor
registries often collect samples from potential donors using buccal swabs or saliva
(both described as saliva in the LOINC term) as part of enrolling them in the registry.
Because these samples do not contain fresh intact red blood cells (RBCs) and traditional
serological RhD blood group typing cannot be done, molecular typing is performed as
part of the screening process to find an appropriate hematopoietic stem cell donor.
Prior to transfusion or transplantation, the presumptive Rh factor result based on
molecular typing must be confirmed using traditional serologic typing. This term was
created for, but not limited in use to, the submitter's lab that performs sequence
analysis of select exons in the RHD gene and predicts the RhD phenotype from the resulting
DNA sequence.;